CSB-Dependent Cyclin-Dependent Kinase 9 Degradation and RNA Polymerase II Phosphorylation during Transcription-Coupled Repair

Publication details

Overview

Citation, authorship and indexing details for this publication.

ART

Authors

Lise-Marie Donnio, Anna Lagarou, Gabrielle Sueur, Pierre-Olivier Mari, Giuseppina Giglia-Mari

Journal

Molecular and Cellular Biology

DOI

10.1128/mcb.00225-18

Open DOI

Scientific fields

Base Excision Repair (BER) DNA damage Neurons Nucleolus Nucleotide Excision Repair (NER) RNA polymerase I and II Spinal Muscular Atrophy (SMA)

Members

Ambra Giglia-Mari

Teams

Nucleolar Dynamic Reorganization in action during DNA Repair (Nu-DyRection)

Summary

DNA lesions block cellular processes such as transcription, inducing apoptosis, tissue failures, and premature aging. To counteract the deleterious effects of DNA damage, cells are equipped with various DNA repair pathways.