Events

Abstract Chromatin within the cell nucleus acquires a complex structure fundamental for genome function. The tridimensional organization of the genome […]

Abstract Sensory neurons have the capacity to grow long distances and high morphological plasticity during development. Upon injury this plasticity […]

Abstract Duchenne muscular dystrophy (DMD) is a rare genetic disease due to the absence of dystrophin from striated muscles. Affected […]

Abstract Maintenance of optimal mitochondrial function plays a crucial role in the regulation of muscle stem cell (MuSC) behavior, but […]

Abstract The second messenger Ca2+ regulates a broad repertoire of cellular processes. Upon physiological stimuli, skeletal muscle mitochondria rapidly and […]

Abstract Ultrastructure expansion microscopy can be useful for structural cell biology, placing specific emphasis on centrioles and their inner scaffold […]

Abstract The function of many organs, including skeletal muscle, depends on its three-dimensional structure. Muscle regeneration therefore requires not only […]

Abstract Functional selectivity, a phenomenon where a ligand favors activation of specific signaling pathways over others, emerges as an innovative […]

Abstract Poly-ADP-Ribose Polymerases (PARPs) are a family of proteins that consume nicotinamide adenine dinucleotide (NAD+; a form of Vitamin B3) […]

Abstract The identification of a point mutation (p.Ser59Leu) in the CHCHD10 gene was the first genetic evidence that mitochondrial dysfunction […]

Abstract Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by a polyglutamine (PolyQ) expansion in the Ataxin-1 […]

Abstract Second messengers, including cAMP, cGMP and Ca2+ are often placed in an integrating position to combine the extracellular cues […]

Abstract Ludo research focuses on the cause, mechanism and treatment options for neurodegenerative diseases. In particular, he studies amyotrophic lateral […]

Abstract

Abstract The compartmentation of signaling processes is accomplished by the assembly of protein complexes called signalosomes. These signaling platforms colocalize […]

Abstract Chromatin architecture impacts on gene expression and defines cell lineage specification. Although epigenetic processes in myogenesis start to be […]

Abstract Among factors involved in muscle homeostasis, emerging relevance is observed for Growth Differentiation Factor 5 (GDF5) which we have […]

Abstract Despite improved in the management, patients with ischemic heart failure still suffer from high morbidity and mortality, and there […]

Abstract Muscle stem cells (muSCs) are crucial for muscle repair, but are increasingly understood to represent a heterogenous population with […]