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Events

crowd of people sitting on chairs inside room
23
Apr
2026
Seminar
Past
External
Huntingtin as a Regulator of Actin Architecture: Insights from Developing Cortical Circuits
Mariacristina Capizzi

Abstract Huntington’s disease (HD) is a monogenic neurodegenerative disorder caused by a CAG expansion in the HTT gene. The work […]

Amphi Hermann (1st floor), Faculté de Médecine Lyon-Est Rockefeller
crowd of people sitting on chairs inside room
07
Nov
2023
Seminar
Past
External
Selective autophagy of phase-separated p62: from molecular mechanism to pathophysiology
Pr Masaaki Komatsu
Médiathèque Paul Zech

Projects

Type:
Category:
Project
Fundamental
National
Better characterize the beneficial role of a variant of the autophagic receptor NDP52 in the context of Alzheimer’s disease
Principal investigator Flavie Strappazzon
Team: Autophagy in pathophysiology
View project
Project
Fundamental
National
Investigate the importance of mitophagy in the context of neurodevelopment
Principal investigator Flavie Strappazzon
Team: Autophagy in pathophysiology
View project
Project
Fundamental
National
Autophagy/mitophagy regulation in striated skeletal muscle and in the context of Myotonic Dystrophy type 1
Principal investigator Flavie Strappazzon
Team: Autophagy in pathophysiology
View project

Publications

2024
Anna Mattioni, Claudia Carsetti, Krenare Bruqi, Valerio Caputo, Valentina Cianfanelli, Maria Giulia ..., A variant of the autophagic receptor NDP52 counteracts phospho-TAU accumulation and emerges as a protective factor for Alzheimer Disease Une variante du récepteur autophagique NDP52 contrecarre l’accumulation de phospho-TAU et apparaît comme un facteur de protection contre la maladie d’Alzheimer, .
2024
Francesco Davide Naso, Krenare Bruqi, Valeria Manzini, Valerio Chiurchiù, Mara D’onofrio, Ivan Ar..., miR-218-5p and doxorubicin combination enhances anticancer activity in breast cancer cells through Parkin-dependent mitophagy inhibition, Cell Death Discovery.
2024
Francesco Davide Naso, Flavie Strappazzon, Combining doxorubicin and miR-218-5p: a new strategy to fight breast cancer?, Autophagy Reports.
2023
Fiorella Faienza, Federica Polverino, Girish Rajendraprasad, Giacomo Milletti, Zehan Hu, Barbara Col..., AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation, Cellular and Molecular Life Sciences.
2023
Ilio Vitale, Federico Pietrocola, Emma Guilbaud, Stuart Aaronson, John Abrams, Dieter Adam, Massimil..., Apoptotic cell death in disease—Current understanding of the NCCD 2023, Cell Death and Differentiation.
2023
Flavie Strappazzon, Habilitation à Diriger des Recherches L’autophagie sélective au coeur de la physiopathologie, .
2022
Alfonso Schiavi, Alessandra Runci, Teresa Maiorino, Francesco Davide Naso, Marta Barenys, Ellen Frit..., Cobalt chloride has beneficial effects across species through a hormetic mechanism, Frontiers in Cell and Developmental Biology.