Events

Abstract Poly-ADP-Ribose Polymerases (PARPs) are a family of proteins that consume nicotinamide adenine dinucleotide (NAD+; a form of Vitamin B3) […]

Abstract The identification of a point mutation (p.Ser59Leu) in the CHCHD10 gene was the first genetic evidence that mitochondrial dysfunction […]

Abstract Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by a polyglutamine (PolyQ) expansion in the Ataxin-1 […]

Abstract Second messengers, including cAMP, cGMP and Ca2+ are often placed in an integrating position to combine the extracellular cues […]

Abstract Ludo research focuses on the cause, mechanism and treatment options for neurodegenerative diseases. In particular, he studies amyotrophic lateral […]

Abstract

Abstract The compartmentation of signaling processes is accomplished by the assembly of protein complexes called signalosomes. These signaling platforms colocalize […]

Abstract Chromatin architecture impacts on gene expression and defines cell lineage specification. Although epigenetic processes in myogenesis start to be […]

Abstract Among factors involved in muscle homeostasis, emerging relevance is observed for Growth Differentiation Factor 5 (GDF5) which we have […]

Abstract Despite improved in the management, patients with ischemic heart failure still suffer from high morbidity and mortality, and there […]

Abstract Muscle stem cells (muSCs) are crucial for muscle repair, but are increasingly understood to represent a heterogenous population with […]

Abstract Our goal is to decipher the mechanisms of cell differentiation in the preimplantation mouse embryo. We are focusing on […]

Abstract My research activity during last decade is dedicated to study the structure, function and physiological importance of KCC2, a […]