Events
Seminars, meetings, defenses and public events connected to the laboratory.
Abstract Poly-ADP-Ribose Polymerases (PARPs) are a family of proteins that consume nicotinamide adenine dinucleotide (NAD+; a form of Vitamin B3) […]
Abstract The identification of a point mutation (p.Ser59Leu) in the CHCHD10 gene was the first genetic evidence that mitochondrial dysfunction […]
Abstract Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by a polyglutamine (PolyQ) expansion in the Ataxin-1 […]
Abstract Second messengers, including cAMP, cGMP and Ca2+ are often placed in an integrating position to combine the extracellular cues […]
Abstract Ludo research focuses on the cause, mechanism and treatment options for neurodegenerative diseases. In particular, he studies amyotrophic lateral […]
Abstract
Abstract The compartmentation of signaling processes is accomplished by the assembly of protein complexes called signalosomes. These signaling platforms colocalize […]
Performance of To the heart of our cells at the Rockefeller medical and pharmacy faculty during the Inserm InScience festival.
Abstract Chromatin architecture impacts on gene expression and defines cell lineage specification. Although epigenetic processes in myogenesis start to be […]
Abstract Among factors involved in muscle homeostasis, emerging relevance is observed for Growth Differentiation Factor 5 (GDF5) which we have […]
Abstract Despite improved in the management, patients with ischemic heart failure still suffer from high morbidity and mortality, and there […]
Abstract Muscle stem cells (muSCs) are crucial for muscle repair, but are increasingly understood to represent a heterogenous population with […]
Abstract Our goal is to decipher the mechanisms of cell differentiation in the preimplantation mouse embryo. We are focusing on […]
Abstract My research activity during last decade is dedicated to study the structure, function and physiological importance of KCC2, a […]
Abstract Neurons with their elaborate and extended morphology must employ homeostatic mechanisms that allow neuronal mitochondria to exist far away […]
Abstract Mitophagy is a form of autophagy (a self-protective mechanism of living cells or organisms under various stressful conditions) that […]
Abstract Coordinated movements, including locomotion, and their control, require proprioceptive information, i.e. information about muscle tone as well as position […]
Abstract Our group is interested in inherited neuromuscular diseases, and in particular in axonal forms of Charcot-Marie-Tooth diseases. Our focus […]
Abstract Satellite cells (SC) are Pax7+ tissue resident muscle stem cells, essential for muscle regeneration. SC are therefore considered as […]
Abstract Angiogenesis, the formation of new blood vessels from existing ones, is initiated by the secretion of growth factors – […]