Members
Patrick Lomonte
Senior Researcher
Tristan Bargain
PHD STUDENT
Damien Blanc
Student
Lucas Bonnefoy
Student
Pierre-Adrien Buffoni
Clinical Assistant Professor
Callum Burnard
MCU
Armelle Corpet
Associate Professor
Mazarine Couturier
PHD STUDENT
Tristan Escure
Doctorant
Clémence Guerriau
Research Assistant
Franceline Juillard
Assistant Professor
Rémi Lebon
PHD STUDENT
Alicia Lopes
Student
Chloé Madras
Research Assistant
Karine Monier
Research Engineer
Rémi Neplaz
PHD STUDENT
Delphine Poncet
Professor
About
Beside the study of the biology of HSV-1, one of the main focus of the team is to understand, at the molecular level and using HSV-1 as a model, some basic aspects of nuclear and chromatin dynamics related to the maintenance of genome integrity and to the regulation of gene expression.
The major research interests of the team LOMONTE are:
- The study of the pathological consequences of the infection of neurons from the peripheral and central nervous systems by the neurotropic virus herpes simplex virus 1 (HSV-1). We essentially focus our research on the establishment of latency and reactivation processes.
- The study of the implication of nuclear architecture, especially promyelocytic leukemia nuclear bodies (PML NBs), in the regulation of latent HSV-1 chromatin features and in chromatin dynamics during the process of senescence.
- The study of the chromatin alterations associated to damage or to genetic pathologies, and potentially linked to genetic instabilities, or motoneurons decay.
