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Explore research projects connected to PGNM teams, facilities and partners, from fundamental mechanisms to translational programmes.

Project
Fundamental
National
Muscle stem cell neighboring
Principal investigator Bénédicte Chazaud
Team: Stem cell environment and skeletal muscle homeostasis
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Project
Fundamental
National
Mutations identification and implication in the physiopathology of cardiomyopathies
Principal investigator Vincent Gache
Principal investigator Marie Abitbol
Team: Architecture du noyau et du cytosquelette musculaire
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Project
Fundamental
National
Neurofilaments in health and neurodegenerative disease
Principal investigator Pascale Bomont
Team: Mechanisms and therapies for neuromuscular diseases
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Project
Fundamental
National
Protecting SMN-Deficient Cells from Oxidative Stress
Principal investigator Ambra Giglia-Mari
Team: Nucleolar Dynamic during DNA Repair in action (Nu-DyRection)
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Project
Fundamental
National
Protein misfolding disorders
Principal investigator Pascal Leblanc
Team: Nerve-muscle interactions
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Project
Fundamental
National
Resistance of skeletal muscle to the metastatic process
Principal investigator Rémi Mounier
Principal investigator Anita Kneppers
Team: Striated Muscle Metabolic Cross-Talk in Health and Disease
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Project
Fundamental
National
Skeletal muscle contraction and myofiber microenvironment 
Principal investigator Julien Gondin
Team: Stem cell environment and skeletal muscle homeostasis
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Project
Fundamental
National
Studying SMN Function in Post-Mitotic Cells
Principal investigator Ambra Giglia-Mari
Team: Nucleolar Dynamic during DNA Repair in action (Nu-DyRection)
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Project
Fundamental
National
TGFβ signaling
Principal investigator Laetitia Mazelin
Team: Nerve-muscle interactions
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Project
Fundamental
National
Therapy for Giant Axonal Neuropathy
Principal investigator Pascale Bomont
Team: Mechanisms and therapies for neuromuscular diseases
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Project
Fundamental
National
Towards a better understanding of the pathophysiology of Friedreich Ataxia (FA) and Cerebellar ataxia with CoQ10 deficiency (ARCA2).
Principal investigator Hélène Puccio
Team: Fundamental and pathophysiological mechanisms implicated in ataxia
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Project
Fundamental
National
Understanding basic mechanisms involved in the regulation of CaV1.1 and of RyR1 function
Principal investigator Vincent Jacquemond
Team: Excitability and calcium signaling in normal and diseased skeletal muscle
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