Rémi Mounier – PGNM

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Delphine Poncet

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Projects

Metabolic regulations of adult muscle stem cell fate

We and others have previously demonstrated a change in metabolism during the muscle stem cell fate. This may serve to […]

A single nucleus approach solving the role of MuSCs in myofiber rejuvenation

The rejuvenation effect of senescent cell removal from aged skeletal muscle can be partially attributed to beneficial effects on the […]

Resistance of skeletal muscle to the metastatic process

Metastasis is the leading cause of death from cancer. Most cancers metastasize to organs such as the lung, liver or […]

Publications

Ilaria Andreana, Ananga Ghosh, Mathieu Repellin, Anita Kneppers, Sabrina Ben Larbi, Federica Tifni, ..., Nanoparticle delivery of AMPK activator 991 prevents its toxicity and improves muscle homeostasis in Duchenne muscular dystrophy, Molecular Therapy - Methods and Clinical Development.

Delia Cicciarello, Sandrine Mouradian, Mélodie Pitchecanin, William Jarassier, Anita Kneppers, Rém..., The AMPKα2/PHF2 axis is critical for turning over lipid droplets during muscle stem cell fate, BioRxiv.

Saugues A, Kneppers A, Mounier R, [Muscle stem cells and metabolism in Duchenne muscular dystrophy, focus on AMPK]., Med Sci (Paris) 2024 Nov; 40 Hors série n° 1(): 60-63.

Mylène Fefeu, Michael Blatzer, Anita Kneppers, David Briand, Pierre Rocheteau, Alexandre Haroche, D..., Serotonin reuptake inhibitors improve muscle stem cell function and muscle regeneration in male mice, Nature Communications.

Marine Lanfranchi, Sozerko Yandiev, Géraldine Meyer-Dilhet, Salma Ellouze, Martijn Kerkhofs, Raphae..., The AMPK-related kinase NUAK1 controls cortical axons branching by locally modulating mitochondrial metabolic functions, Nature Communications.

Ever Espino-Gonzalez, Emilie Dalbram, Rémi Mounier, Julien Gondin, Jean Farup, Niels Jessen, Jonas ..., Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments, Cell Metabolism.

Osseni A, Ravel-Chapuis A, Belotti E, Scionti I, Gangloff YG, Moncollin V, Mazelin L, Mounier R, Leb..., Pharmacological inhibition of HDAC6 improves muscle phenotypes in dystrophin-deficient mice by downregulating TGF-β via Smad3 acetylation., Nat Commun 2022 Nov; 13(1): 7108.