Vincent Jacquemond – PGNM

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Luc-Alban Lhoste

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Projects

Understanding basic mechanisms involved in the regulation of CaV1.1 and of RyR1 function

Vincent Jacquemond

Disease Mutations Disrupting Excitability and EC Coupling in Skeletal Muscle

Demonstrating how excitability and/or EC coupling are altered by specific disease mutations affecting the genes encoding CaV1.1, RyR1 and also […]

Vincent Jacquemond

Publications

Jaque-Fernandez F, Demesmay L, Idoux R, Berthier C, Jacquemond V, Allard B, Mn quenching in activated zebrafish muscle fibers does not result from store-operated Ca entry., J Gen Physiol 2026 Jan; 158(1): .

Léa Demesmay, Romane Idoux, Christine Berthier, Claire Bernat, Léon Espinosa, Vincent Jacquemond, ..., Zebrafish fast muscle contractions avoid the mammalian requirement for voltage-gated Na+ channels, PLoS Biology.

Margaux Melka, Ludivine Rotard, Caroline Benstaali, Julie Brocard, Benoit Giannesini, Fanny Jouve, L..., Limited pre-clinical relevance of the heterozygous RYR1-I4895T/+ mouse model due to its mild phenotype, Journal of Neuromuscular Diseases.

Guiraud A, Couturier N, Christin E, Castellano L, Daura M, Kretz-Remy C, Janin A, Ghasemizadeh A, De..., SH3KBP1 promotes skeletal myofiber formation and functionality through ER/SR architecture integrity., EMBO Rep 2025 Apr; 26(8): 2166-2191.

Jonathan Schreiber, Ludivine Rotard, Yves Tourneur, Aude Lafoux, Christine Berthier, Bruno Allard, C..., Reduced voltage-activated Ca2+ release flux in muscle fibers from a rat model of Duchenne dystrophy, Journal of General Physiology.

Romane Idoux, Chlo Exbray-Héritier, Frédéric Sohm, Francisco Jaque-Fernandez, Elisabeth Vaganay, ..., A mechano-and heat-gated two-pore domain K + channel controls excitability in adult zebrafish skeletal muscle, Proceedings of the National Academy of Sciences of the United States of America.

Francisco Jaque-Fernandez, Bruno Allard, Laloé Monteiro, Aude Lafoux, Corinne Huchet, Enrique Jaimo..., Probenecid affects muscle Ca2+ homeostasis and contraction independently from pannexin channel block, Journal of General Physiology.

Svahn J, Coudert L, Streichenberger N, Kraut A, Gravier-Dumonceau-Mazelier A, Rotard L, Calemard-Mic..., Immune-Mediated Rippling Muscle Disease Associated With Thymoma and Anti-MURC/Cavin-4 Autoantibodies., Neurol Neuroimmunol Neuroinflamm 2023 Jan; 10(1): .

Idoux R, Bretaud S, Berthier C, Ruggiero F, Jacquemond V, Allard B, Superfast excitation-contraction coupling in adult zebrafish skeletal muscle fibers., J Gen Physiol 2022 Sep; 154(9): .

Alireza Ghasemizadeh, Emilie Christin, Alexandre Guiraud, Nathalie Couturier, Valérie Risson, Emman..., Skeletal muscle MACF1 maintains myonuclei and mitochondria localization through microtubules to control muscle functionalities, .