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Publications
2025
[Human organoids and their clinical promise in the neuromuscular field].,
Med Sci (Paris) 2025 Nov; 41 Hors série n° 2(): 14-18.
2025
Muscle mTOR controls iron homeostasis and ferritinophagy via NRF2, HIFs and AKT/PKB signaling pathways.,
Cell Mol Life Sci 2025 Apr; 82(1): 178.
2025
Muscle fibroblasts and stem cells stimulate motor neurons in an age and exercise-dependent manner.,
Aging Cell 2025 Mar; 24(3): e14413.
2025
Enhanced secretion of the amyotrophic lateral sclerosis ALS-associated misfolded TDP-43 mediated by the ER-ubiquitin specific peptidase USP19.,
Cell Mol Life Sci 2025 Feb; 82(1): 76.
2025
Delivery of Prime editing in human stem cells using pseudoviral NanoScribes particles.,
Nat Commun 2025 Jan; 16(1): 397.
2025
Targeting histone deacetylase 6 (HDAC6) in Duchenne muscular dystrophy: New insights into therapeutic potential.,
Acta Physiol (Oxf) 2025 Jan; 241(1): e14256.
2024
Mitochondrial disorders are associated with morphological neuromuscular junction defects.,
Neuromuscul Disord 2024 Dec; 45(): 105235.
2024
Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for In Vivo Mouse Studies.,
J Med Chem 2024 Jul; 67(13): 11296-11325.
2024
The new missense G376V-TDP-43 variant induces late-onset distal myopathy but not amyotrophic lateral sclerosis.,
Brain 2024 May; 147(5): 1768-1783.
2024
LSD1 controls a nuclear checkpoint in Wnt/β-Catenin signaling to regulate muscle stem cell self-renewal.,
Nucleic Acids Res 2024 Apr; 52(7): 3667-3681.
2024
H2A.Z is involved in premature aging and DSB repair initiation in muscle fibers.,
Nucleic Acids Res 2024 Apr; 52(6): 3031-3049.
2024
Genetic characterization of non-5q proximal spinal muscular atrophy in a French cohort: the place of whole exome sequencing.,
Eur J Hum Genet 2024 Jan; 32(1): 37-43.
2023
Spatial Transcriptomics Reveals Signatures of Histopathological Changes in Muscular Sarcoidosis.,
Cells 2023 Nov; 12(23): .
2023
Nucleolar reorganization after cellular stress is orchestrated by SMN shuttling between nuclear compartments.,
Nat Commun 2023 Nov; 14(1): 7384.
2023
H syndrome mimicking Erdheim Chester disease: new entity and therapeutic perspectives.,
Haematologica 2023 Aug; 108(8): 2255-2260.
2023
Homozygous COQ7 mutation: a new cause of potentially treatable distal hereditary motor neuropathy.,
Brain 2023 Aug; 146(8): 3470-3483.
2023
Interplay between PML NBs and HIRA for H3.3 dynamics following type I interferon stimulus.,
Elife 2023 May; 12(): .
2023
Reply: Biallelic variants in the COQ7 gene cause distal hereditary motor neuropathy in two Chinese families.,
Brain 2023 May; 146(5): e31-e32.
2023
Hydroxypropyl-β-Cyclodextrin Depletes Membrane Cholesterol and Inhibits SARS-CoV-2 Entry into HEK293T-ACEhi Cells.,
Pathogens 2023 Apr; 12(5): .
2023
MBNL-dependent impaired development within the neuromuscular system in myotonic dystrophy type 1.,
Neuropathol Appl Neurobiol 2023 Feb; 49(1): e12876.
2023
Chromodomain on Y-like 2 (CDYL2) implicated in mitosis and genome stability regulation via interaction with CHAMP1 and POGZ.,
Cell Mol Life Sci 2023 Jan; 80(2): 47.
2023
Immune-Mediated Rippling Muscle Disease Associated With Thymoma and Anti-MURC/Cavin-4 Autoantibodies.,
Neurol Neuroimmunol Neuroinflamm 2023 Jan; 10(1): .
2023
Repurposing pentamidine using hyaluronic acid-based nanocarriers for skeletal muscle treatment in myotonic dystrophy.,
Nanomedicine 2023 Jan; 47(): 102623.
2022
[HDAC6, a very specific deacetylase with a potential therapeutic role].,
Med Sci (Paris) 2022 Dec; 38 Hors série n° 1(): 6-12.
2022
Expanding the phenotypic variability of MORC2 gene mutations: From Charcot-Marie-Tooth disease to late-onset pure motor neuropathy.,
Hum Mutat 2022 Dec; 43(12): 1898-1908.
2022
Novel Intronic Mutation in VMA21 Causing Severe Phenotype of X-Linked Myopathy with Excessive Autophagy-Case Report.,
Genes (Basel) 2022 Nov; 13(12): .
2022
Pharmacological inhibition of HDAC6 improves muscle phenotypes in dystrophin-deficient mice by downregulating TGF-β via Smad3 acetylation.,
Nat Commun 2022 Nov; 13(1): 7108.
2022
Severe congenital myasthenic syndromes caused by agrin mutations affecting secretion by motoneurons.,
Acta Neuropathol 2022 Oct; 144(4): 707-731.
2022
Simple Methods for Permanent or Transient Denervation in Mouse Sciatic Nerve Injury Models.,
Bio Protoc 2022 Jun; 12(11): .
2022
Hypothalamic-pituitary-adrenal axis activation and glucocorticoid-responsive gene expression in skeletal muscle and liver of Apc mice.,
J Cachexia Sarcopenia Muscle 2022 Jun; 13(3): 1686-1703.
2022
Microrchidia CW-Type Zinc Finger 2, a Chromatin Modifier in a Spectrum of Peripheral Neuropathies.,
Front Cell Neurosci 2022 ; 16(): 896854.
2022
Epigenetic Control of Muscle Stem Cells: Focus on Histone Lysine Demethylases.,
Front Cell Dev Biol 2022 ; 10(): 917771.
2021
Drosophila Nesprin-1 Isoforms Differentially Contribute to Muscle Function.,
Cells 2021 Nov; 10(11): .
2021
MACF1 controls skeletal muscle function through the microtubule-dependent localization of extra-synaptic myonuclei and mitochondria biogenesis.,
Elife 2021 Aug; 10(): .
2020
Regulation of Gene expression at the neuromuscular Junction.,
Neurosci Lett 2020 Sep; 735(): 135163.
2020
HDAC6 regulates microtubule stability and clustering of AChRs at neuromuscular junctions.,
J Cell Biol 2020 Aug; 219(8): .
2020
H2A.Z is dispensable for both basal and activated transcription in post-mitotic mouse muscles.,
Nucleic Acids Res 2020 May; 48(9): 4601-4613.
2020
Mitochondrial function in skeletal myofibers is controlled by a TRF2-SIRT3 axis over lifetime.,
Aging Cell 2020 Mar; 19(3): e13097.
2019
Phosphorylated and aggregated TDP-43 with seeding properties are induced upon mutant Huntingtin (mHtt) polyglutamine expression in human cellular models.,
Cell Mol Life Sci 2019 Jul; 76(13): 2615-2632.
2019
Discovery of BNC375, a Potent, Selective, and Orally Available Type I Positive Allosteric Modulator of α7 nAChRs.,
ACS Med Chem Lett 2019 May; 10(5): 754-760.
2019
Lack of muscle mTOR kinase activity causes early onset myopathy and compromises whole-body homeostasis.,
J Cachexia Sarcopenia Muscle 2019 Feb; 10(1): 35-53.
2019
Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons.,
J Vis Exp 2019 Jan; (143): .
2019
Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins.,
Nat Commun 2019 Jan; 10(1): 45.
2018
LPS-induced histone H3 phospho(Ser10)-acetylation(Lys14) regulates neuronal and microglial neuroinflammatory response.,
Brain Behav Immun 2018 Nov; 74(): 277-290.
2018
Increased Serpina3n release into circulation during glucocorticoid-mediated muscle atrophy.,
J Cachexia Sarcopenia Muscle 2018 Oct; 9(5): 929-946.
2018
Correction to: Cellular mechanisms responsible for cell-to-cell spreading of prions.,
Cell Mol Life Sci 2018 Jul; 75(14): 2575.
2018
Cellular mechanisms responsible for cell-to-cell spreading of prions.,
Cell Mol Life Sci 2018 Jul; 75(14): 2557-2574.
2018
Prestressed cells are prone to cytoskeleton failures under localized shear strain: an experimental demonstration on muscle precursor cells.,
Sci Rep 2018 Jun; 8(1): 8602.
2017
Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal death.,
Acta Neuropathol Commun 2017 Jul; 5(1): 55.
2017
LSD1 Controls Timely MyoD Expression via MyoD Core Enhancer Transcription.,
Cell Rep 2017 Feb; 18(8): 1996-2006.
2017
Isolation of Exosomes and Microvesicles from Cell Culture Systems to Study Prion Transmission.,
Methods Mol Biol 2017 ; 1545(): 153-176.
2016
[NeuroMyoGene Institute: a Franco-Canadian partnership promoting research in neuromuscular disorders].,
Med Sci (Paris) 2016 Nov; 32 Hors série n°2(): 55-56.
2016
Latency Entry of Herpes Simplex Virus 1 Is Determined by the Interaction of Its Genome with the Nuclear Environment.,
PLoS Pathog 2016 Sep; 12(9): e1005834.
2016
mTOR inactivation in myocardium from infant mice rapidly leads to dilated cardiomyopathy due to translation defects and p53/JNK-mediated apoptosis.,
J Mol Cell Cardiol 2016 Aug; 97(): 213-25.
2016
A transgenic mouse expressing CHMP2Bintron5 mutant in neurons develops histological and behavioural features of amyotrophic lateral sclerosis and frontotemporal dementia.,
Hum Mol Genet 2016 Aug; 25(15): 3341-3360.
2016
Time-lapse scanning surface plasmon microscopy of living adherent cells with a radially polarized beam.,
Appl Opt 2016 Feb; 55(6): 1216-27.
2015
PAK1 and CtBP1 Regulate the Coupling of Neuronal Activity to Muscle Chromatin and Gene Expression.,
Mol Cell Biol 2015 Dec; 35(24): 4110-20.
2015
Comparison of two next-generation sequencing kits for diagnosis of epileptic disorders with a user-friendly tool for displaying gene coverage, DeCovA.,
Appl Transl Genom 2015 Dec; 7(): 19-25.
2015
Efficient inhibition of infectious prions multiplication and release by targeting the exosomal pathway.,
Cell Mol Life Sci 2015 Nov; 72(22): 4409-27.
2015
MuSK frizzled-like domain is critical for mammalian neuromuscular junction formation and maintenance.,
J Neurosci 2015 Mar; 35(12): 4926-41.
2015
Histone deacetylase 6 is a FoxO transcription factor-dependent effector in skeletal muscle atrophy.,
J Biol Chem 2015 Feb; 290(7): 4215-24.
2014
Myostatin gene inactivation prevents skeletal muscle wasting in cancer.,
Cancer Res 2014 Dec; 74(24): 7344-56.
2014
Drosophila Nesprin-1 controls glutamate receptor density at neuromuscular junctions.,
Cell Mol Life Sci 2014 Sep; 71(17): 3363-79.
2014
Anti-agrin autoantibodies in myasthenia gravis.,
Neurology 2014 Jun; 82(22): 1976-83.
2014
Phosphorylation of NBR1 by GSK3 modulates protein aggregation.,
Autophagy 2014 Jun; 10(6): 1036-53.
2014
Diffraction phase microscopy: retrieving phase contours on living cells with a wavelet-based space-scale analysis.,
J Biomed Opt 2014 Mar; 19(3): 36007.
2013
Muscle histone deacetylase 4 upregulation in amyotrophic lateral sclerosis: potential role in reinnervation ability and disease progression.,
Brain 2013 Aug; 136(Pt 8): 2359-68.
2013
A mutation causes MuSK reduced sensitivity to agrin and congenital myasthenia.,
PLoS One 2013 ; 8(1): e53826.
2012
CKIP-1 regulates mammalian and zebrafish myoblast fusion.,
J Cell Sci 2012 Aug; 125(Pt 16): 3790-800.
2012
Functional mechanisms of the cellular prion protein (PrP(C)) associated anti-HIV-1 properties.,
Cell Mol Life Sci 2012 Apr; 69(8): 1331-52.
2012
Wnt4 participates in the formation of vertebrate neuromuscular junction.,
PLoS One 2012 ; 7(1): e29976.
2011
Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function.,
Proc Natl Acad Sci U S A 2011 Dec; 108(51): 20808-13.
2010
Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor.,
Mol Cell Proteomics 2010 Jul; 9(7): 1578-93.
2010
DHPR alpha1S subunit controls skeletal muscle mass and morphogenesis.,
EMBO J 2010 Feb; 29(3): 643-54.
2009
Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.,
J Cell Biol 2009 Dec; 187(6): 859-74.
2009
Identification of an agrin mutation that causes congenital myasthenia and affects synapse function.,
Am J Hum Genet 2009 Aug; 85(2): 155-67.
2009
Silencing rapsyn in vivo decreases acetylcholine receptors and augments sodium channels and secondary postsynaptic membrane folding.,
Neurobiol Dis 2009 Jul; 35(1): 14-23.
2009
Muscle mitochondrial uncoupling dismantles neuromuscular junction and triggers distal degeneration of motor neurons.,
PLoS One 2009 ; 4(4): e5390.
2007
Postsynaptic chromatin is under neural control at the neuromuscular junction.,
EMBO J 2007 Feb; 26(4): 1117-28.
2006
NOV/CCN3 impairs muscle cell commitment and differentiation.,
Exp Cell Res 2006 Jun; 312(10): 1876-89.
2005
Calcineurin-NFAT signaling, together with GABP and peroxisome PGC-1{alpha}, drives utrophin gene expression at the neuromuscular junction.,
Am J Physiol Cell Physiol 2005 Oct; 289(4): C908-17.
2005
Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression.,
Nat Neurosci 2005 Mar; 8(3): 313-21.
2005
[Pathophysiological characterization of congenital myasthenic syndromes: the example of mutations in the MUSK gene].,
J Soc Biol 2005 ; 199(1): 61-77.
2004
14-3-3 gamma associates with muscle specific kinase and regulates synaptic gene transcription at vertebrate neuromuscular synapse.,
Proc Natl Acad Sci U S A 2004 Dec; 101(52): 18189-94.
2004
MUSK, a new target for mutations causing congenital myasthenic syndrome.,
Hum Mol Genet 2004 Dec; 13(24): 3229-40.
2004
Thrombin reduces MuSK and acetylcholine receptor expression along with neuromuscular contact size in vitro.,
Eur J Neurosci 2004 Apr; 19(8): 2099-108.
2004
Role for the pleckstrin homology domain-containing protein CKIP-1 in phosphatidylinositol 3-kinase-regulated muscle differentiation.,
Mol Cell Biol 2004 Feb; 24(3): 1245-55.
2004
Conditional gene knock-down by CRE-dependent short interfering RNAs.,
EMBO Rep 2004 Feb; 5(2): 178-82.
2003
Synapse-specific gene expression at the neuromuscular junction.,
Ann N Y Acad Sci 2003 Sep; 998(): 53-65.
2003
Localization of the RNA-binding proteins Staufen1 and Staufen2 at the mammalian neuromuscular junction.,
J Neurochem 2003 Aug; 86(3): 669-77.
2003
Thrombin downregulates muscle acetylcholine receptors via an IP3 signaling pathway by activating its G-protein-coupled protease-activated receptor-1.,
J Cell Physiol 2003 Jul; 196(1): 105-12.
2003
Design and synthesis of gamma-dipeptide derivatives with submicromolar affinities for human somatostatin receptors.,
Angew Chem Int Ed Engl 2003 Feb; 42(7): 776-8.
2002
Expression of mutant Ets protein at the neuromuscular synapse causes alterations in morphology and gene expression.,
EMBO Rep 2002 Nov; 3(11): 1075-81.