About
The dysregulation of mTOR signaling (mechanistic Target of Rapamycin) in skeletal muscle is a shared feature among several myopathies, therapeutic interventions (e.g., statins and glucocorticoids), and aging. Our laboratory has demonstrated a critical role of mTOR in the regulation of muscle integrity and whole-body homeostasis in mice. Overall, our work aims to understand the contribution of mTOR signaling in the pathophysiology of neuromuscular disorders.